Wine does work on MAC. I have installed it on mine along with e-Sword and it works without pain. The link below gives details of how it can work. Wine is best known for working on Linux, but it is also for MAC. David Baumgold's article may be of assistance.
As for installing e-Sword, I followed the instructions found on the "Pentecostal Blogger". This following link will take you there:
There is also this thread here:
Hope this helps!